TABLE 2. Plasma homovanillic acid studies in schizophrenia: baseline pHVA as prediction of treatment response a

Reference Subjects (N) Drug-free Duration Result
Bowers et al. (52) Psychosis (85)
    7
 10 days Baseline pHVA correlated with outcome at day 10
Davila et al. (45) SCZ (14)
    37
 4 weeks Baseline pHVA similar in responders and nonresponders
Bowers et al. (95) Psychosis (47)
    7
 10 days Baseline pHVA higher in responders
Van Putten et al. (53) SCZ (22)
    28
 6 weeks Baseline pHVA higher in responders
Javaid et al. (55) SCZ (25)
    ¾
 4 weeks Baseline pHVA similar in responders and nonresponders
Chang et al. (49) SCZ (33)
    28
 6 weeks Baseline pHVA higher in responders
Davidson et al.

(50),(51)

SCZ (20)
    14

5 weeks

Baseline pHVA higher in responders

Mazure et al. (54) Psychosis (37)
    7
 10 days Baseline pHVA higher in responders

aAbbreviations are defined in footnote a of Table 1

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published 2000