Figure 11.

Synergistic action between D1 and D2 dopamine receptors in alleviating the immobility of a Parkinson's diseased patient. Lisuride has a predominantly D2 action (see Table 2) while L-DOPA results in the synthesis of dopamine, which activates both D1 and D2. The patient's mobility is sustained on the combined activation of D1 and D2. (adapted from ref. 124)

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published 2000