TABLE 1.  Genetically variable enzymes of

drug metabolism a

Butyryl cytochromes

Serum paroxanase/arylesteraseb

Debrisoquin-sparteine oxidase (CYP2D6)b

Mephenytoin hydroxylase (CYPmp)b

Dopamine-b-hydroxylase

Catalase

Superoxide dismutase

Monoamine oxidase

Alcohol dehydrogenaseb

Aldehyde dehydrogenaseb

Dihydropyrimidine dehydrogenase (DPD)

N-Acetyltransferase (NAT2)b

Glucuronyl transferase (UDPGT)b

Thiol methyltranferaseb

Thiopurine methyltransferase

Phenol sulfotransferase (thermal stability)b

Glutathione-S-transferase (class mu)b

a Adapted from ref.  36.
b Indicates polymorphic variation.
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published 2000