Reference

Number of cases

(Total)

M:F ratio

Age at onset (years)

Age at presentation

(years)

Core symptoms

Comorbidity

Treatment

Outcome

Period cases reviewed

Comments

Lesser et al. 1960

3 (15)

not reported

before age 13

not reported

+

hysterical

obsessive-compulsive

schizoid

hospitalization

"good"

1960

Youngest 10 years

Blitzer et al. 1961

9 (15)

3:15

7-14

10-16

+

anxiety

anger

hospitalization

1/27 died

1960-68

9 premenarchal

Warren

1968

8 prepubertal

4 premenarchal

(20)

no boys

10-15

12-16

less weight loss

+

depression

anxiety

tension

hospitalization

2/8 prepubertal  pts. died

1949-64

10% of all patients admitted to Maudsley Hospital

Galdston

1972

? (50) 8 - 16 years

9:41

number of prepubertal cases not reported

number of prepubertal cases not reported

3 suicidal

+

moderate depression

euphoria

hospitalization

psychotherapy

all discharged with weight gain

1960-72

Children's Hospital Boston

Halmi

1974

7 (94)

6:88

8% <10 years

29% 10-15

41% 16-25

25% >25

+

anxiety

obsessive-compulsive

depression

hospitalization

not reported

1920-72

Hospitals

U. of Iowa

Goetz et al. 1977

? (30)

2:28

9.5-16

+

hysterical

obsessive-compulsive

schizoid

hospitalization

good

1954-70

Children's Hospital

Pittsburgh

Irwin

1984

13 (54)

males excluded

?

9-12

less weight loss  +

depression

hospitalization

not reported

1960-80

7% under age 10

Hawley

1985

10 prepubescent

7 pubescent

(21)

4:21

7.2-13.5

not reported

+

not reported

hospitalization

67% good outcome

1964-82

All boys prepubertal

Children's Hospital

Birmingham

Jacobs & Isaacs

1986

20

6:14

7.2-13.9

not reported

+

sexual anxiety

disturbed peer relationships

hospitalization

poor prognosis

low social class

family psychopathology

1963-81

Maudsley Hospital

Fosson et al. 1987

23 prepubertal (48)

13:35

7.7-13.7

8.2-13.9

+

depression

family conflict

hospitalization

good

1960-84

Hospital for Sick Children

7:16 prepubescent

6:14 pubescent

Higgs et al. 1989

(27)

8:19

8-16

not reported

+

Higher obsessionality than comparison group

hospitalization

50% good or intermediate outcome, boys better outcome

1958-84

Children's Hospital Manchester

Atkins and Silber 1990

9 (21)

0:21

9 Tanner stage I

7-12

+ in 16

71% additional diagnosis

hospitalization

all prepubertal cases good outcome

1978-89

Children's Hospital

Gowers et al. 1991

30 premenarchal

males excluded

13.6±2.2

16.3±5.3

+

not described

hospitalization

anxiety about pubertal development

not indicated

St. George's Hospital