TABLE 5.  Spearman correlations between parietal/prefrontal rCMRglc ratios and parietal/prefrontal neuropsychological test score discrepancies in AD patients a,b

 

Parietal/prefrontal metabolic ratio

 

Controls (14 -17)c

Mild AD (10) c

Moderate AD (14)

Neuropsychological discrepancy

Right

Left

Right

Left

Right

Left

Arithmetic versus

 

 

 

 

 

 

Verbal fluency

- 0.02

0.00

- 0.14

0.04

0.63 *

0.57 *

Attention (Trail A)

- 0.34

-0.08

- 0.02

- 0.21

0.43

0.46

 

 

 

 

 

 

 

Verbal comprehension versus

 

 

 

 

 

 

Verbal fluency

0.00

0.03

- 0.30

- 0.06

0.66 *

0.67 *

Attention (Trail A)

- 0.12

0.11

0.04

- 0.01

0.51

0.56 *

 

 

 

 

 

 

 

Drawing versus

 

 

 

 

 

 

Verbal fluency

- 0.02

0.11

-0.02

0.22

0.66 *

0.57

Attention (Trail A)

- 0.21

0.21

0.42

0.32

0.44

0.43

 

 

 

 

 

 

 

Immediate memory span for visuospatial

 

 

 

 

 

 

location (block tapping) versus

 

 

 

 

 

 

Verbal fluency

0.16

0.05

- 0.25

-0.11

0.62 *

0.54

Attention (Trail A)

0.14

0.32

0.26

0.11

0.73 **

0.72 **

   a Neuropsychological discrepancy is rank on a test of arithmetic, syntax comprehension, and extended range drawing minus rank on controlled word association or attentional trailmaking (Trail A) test score.

Scanditronix PC 1024 -7B data from ref.32.

   b Spearman correlation coefficient in AD differs from control: * p < 0.05 ; * * p < 0.01.

   c Number of subjects are in parentheses.  

 

 

 

 

published 2000