FIG. 2
Diagram showing the structural domains of APP and the position of disease causing mutations with respect to the sites of cleavage by proteolytic processing enzymes (a, b, and g secretase). The black box represents b-A4, and {ewc MVIMG, MVIMAGE,!vertline.bmp} {ewc MVIMG, MVIMAGE,!vertline.bmp} represents the plasma membrane.
Back to Chapter

published 2000