Figure 2

Positron emission tomographic scans demonstrating glucose metabolic rate of each area of brain, divided by that of whole brain (red>yellow>green>blue). Scans are from five middle-aged women and illustrate findings in left dorsal anterolateral prefrontal cortex (arrows). NL CONT indicates normal control; UNI DEP, unipolar depression; BI DEP, bipolar depression; OCC, obsessive-compulsive disorder without secondary major depression; and OCD+DEP, obsessive-compulsive disorder with secondary major depression. Depressed patients show similar reduced prefrontal metabolism. With permission from Baxter et al. 1989 (7).

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published 2000