FIG. 6
A general four-compartment model of radiotracer behavior in the brain; F is the cerebral blood flow; Ca is the arterial concentration; Cv is the venous concentration; C1 is the capillary concentration; C2 is the intracerebral free concentration; C´2 is the intracerebral nonspecifically bound concentration; C3 is the specifically bound concentration; k1k6 are fractional rate constants that describe the direction and rate of tracer exchange between compartments.
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published 2000