| Figure 2 |
|
|
| The prosomeric model of forebrain patterning, defined
by gene expression boundaries. Schematic representation of the
expression of six genes-Dlx2, Gbx2, Nkx2.1, Nkx2.2, Otx2, and sonic hedgehog (Shh) in the neural plate (E8.5), and the neural
tube (E10.5 and E12.5) of the embryonic mouse brain. The provisional transverse
and longitudinal boundaries are indicated as thin black lines. D, diencephalon,
E, eyes, H, rhomboencephalon-hindbrain, I, isthmus, M, mesencephalon-midbrain,
os, optic stalk, P, prosomere, r, rhombomere, sc, spinal cord, SP, secondary
prosencephalon. From Rubenstein
et al. (1994) reproduced with permission. |
published 2000