Figure 11. Section through the testis of a rat treated with saline (A) or with the LHRH agonist [D-Ala6]-LHRH-EA (B) (100 mg, twice weekly for 4 weeks). Most tubules are representing degenerative changes. In same tubules ('), all germinal and sertoli cells have completely disappeared. Leydig cells (L) have a normal appearance. (From ref. 133.).