|
|
Transmitter |
|
Receptor |
Emetic |
|
Emetic |
System |
Receptor |
Location |
Antagonist |
|
|
|
|
|
|
|
Cisplatin |
Serotonin |
5-HT3 |
Viceral
Afferents |
Ondansetron |
|
|
|
|
Area Postrema |
|
|
|
|
|
|
|
|
Apomorphine |
Dopamine |
D2 |
CTZ |
Metopimazine |
|
|
|
|
Area
Postrema |
|
|
|
|
|
|
|
|
Motion |
Histamine |
H1 |
Vestibular |
Meclizine |
|
|
|
|
Afferents |
|
|
|
|
|
Area
Postrema |
|
|
|
|
|
|
|
|
Motion |
Acetylcholine |
M1 |
Vestibular |
Scopolamine |
|
|
|
M2 |
Apparatus |
|
|
|
|
|
Cortex |
|
published 2000