Left: Percent of patients in each treatment group
who experienced nausea in the first 24 hrs. after recovery from anaesthesia
for major gynaecological surgery. Ondansitron
8 mgm was given 1 hr. before anaesthesia, and then again 8 and 16 hours
later. (Adapted from Kenny et
al. - 40). Right: Treatment dosage was ondansetron 8 mgm twice
a day with 30 mg. metopimazine 4 times a day or ondansitron 8 mgm twice
a day with placebo 4 times a day. Chemotherapy
was given after the first dose. Data is for ratings of nausea over the first day of treatment.
(Adapted from Herrstedt et al. - 37).