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Populations and subpopulations
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Signala
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Newer namesb
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Comments
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5-HT1
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5-HT1A
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(-)AC
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5-HT1A
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Cloned and pharmacological 5-HT1A sites.
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5-HT1B
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(-)AC
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5-HT1B
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Rodent homolog of human 5-HT1Db
receptors.
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5-HT1D
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5-HT1Bb
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A mouse homolog of human 5-HT1Db
receptors.
Sites identified in binding studies using brains homogenates.
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5-HT1Da
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(-)AC
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5-HT1Da
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A cloned human 5-HT1D subpopulation.
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5-HT1Db
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(-)AC
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5-HT1Db
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A second cloned human 5-HT1D subpopulation.
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5-HT1E
5-HT1Ea
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(-)AC
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5-HT1Eb
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Sites identified in binding studies using brain homogenates.
An alternate name for cloned human 5-HT1E receptors.
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5-HT1F
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5-HT1F
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A cloned human 5-HT1-like receptor population.
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5-HT1P
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A peripheral 5-HT1-like receptor population.
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5-HT1S
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5-HT1-like receptors found in spinal cord; not well studied.
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5-HT2
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5-HT2
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PI
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5-HT2A
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Original "5-HT2" (5-HT2a)
receptors.
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5-HT2F
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PI
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5-HT2B
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5-HT2-like receptors in rat fundus.
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5-HT1C
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PI
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5-HT2C
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Original 5-HT1C (5-HT2b)
receptors.
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5-HT3
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5-HT3
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IC
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5-HT3
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An ion channel receptor.
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5-HT4
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5-HT4
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(+)AC
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5-HT4
5-HT4S
5-HT4L
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5-HT4 population originally described in functional
studies.
Short form of cloned rat 5-HT4 receptors.
Long form of cloned rat 5-HT4 receptors.
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5-HT5
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5-HT5A
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?C
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5-HT5A
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Cloned mouse, rat and human 5-HT5 receptors.
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5-HT5B
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?
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5-HT5B
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Cloned mouse and rat 5-HT5A-like receptor.
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5-HT6
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5-HT6
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(+)AC
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5-HT6
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Cloned rat and human 5-HT receptor.
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5-HT7
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5-HT7
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(+)AC
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5-HT7
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Cloned rat, mouse, guinea pig and human 5-HT receptors.
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