|
Present nomenclature
|
Pharmacologically identified as:
|
Cloned as:
|
G protein
|
Second Messenger
|
Subtype-selection Agonists
|
Subtype-selective Antagonists
|
Human MrNA
|
Human protein
|
|
a1A
|
a1A
|
a1c
|
Gq
G11
G14
|
Ca2+
PLC
PLA2
PLD
|
oxymetazoline
|
5-methyluradipil
(+)-niguldipine
A-61603
SNAP-5089
KMD-3213
RS 17053
WB4101
|
Cerebellum
cerebral cortex
pituitary
|
Cerebral cortex
(frontal, temporal, parietal lobe)
|
|
a1B
|
a1B
|
a1b
|
Gq
G11
G14
G16
Gh
|
Same as above
|
|
AH11110A
spiperone
|
Cerebellum
cerebral cortex
|
Cerebral cortex
(frontal, temporal, parietal lobe)
|
|
a1D
|
Not discovered
|
a1a
a1d a1a/d
|
Gq
G11
|
Same as above
|
|
BMY 7378
SKF 105854
(+)-discretamine
|
Cerebellum cerebral cortex
|
Not determined
|