Figure 1.
Schematic representation of a synapse showing vesicular release of biogenic amines and transmitter reuptake by presynaptic transporters. Transmitter movements by transporters are given bidirectional arrows to indicate a capacity for both influx and efflux. Transmitter vesicles within the presynaptic cytoplasm are shown colocalized with large dense-core secretory granules containing neuropeptides. NT, neurotransmitter undergoing uptake and being packaged into synaptic vesicles for subsequent release; R, receptors on presynaptic and postsynaptic membranes.
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published 2000