TABLE 1.  PROTEIN KINASES IN THE BRAIN

PROTEIN SERINE-THREONINE KINASES

      Second messenger-dependent protein kinases

            cAMP-dependent protein kinase

            cGMP-dependent protein kinase

            Ca²⁺/calmodulin-dependent protein kinases

            Protein kinase C

      Second messenger-independent protein kinases

            MAP kinases (or ERKs)

            cdc kinases

            casein kinases

            raf kinase

            rsk (ribosomal S6 kinase)

            mos kinase

            ste kinase

            many others

PROTEIN TYROSINE KINASES

      Receptor-associated kinases

            Insulin receptor

            Epidermal growth factor receptor

            Neurotrophin receptors (trk)

            many others

      Not receptor-associated

            src

            yes

            fes

            Jak

Back to Chapter