Figure 12.
The binding of [11C]raclopride to D2 receptors in post-mortem schizophrenia striata is not sensitive to the addition of guanine nucleotide. This indicates that schizophrenia tissues have either a low level of dopamine in the synapse or an abnormality in the coupling between the D2 receptor and its G protein. (Adapted from refs. 158,161)
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published 2000