TABLE 1. Acquisition and retention of a delayed alternation task. Effect of different DA terminal regions in corticolimbic systems
 

Errors in the 60 first trials

 
 

(mean ± SEM)

Trials for learning criterion

Group

Preoperative

Postoperative

Preoperative

Postoperative

Control

17.6 ± 0.9

6.9 ± 8.4

190.0 ± 8.4

86.7 ± 11.4

Anterior striatum

17.2 ± 0.7

18.2 ± 3.0**,a

183.3 ± 46.4

2132.3 ± 46.4*,a

Prefrontal cortex

17.6 ± 0.9

17.3 ± 2.7**,a

193.3 ± 16.1

153.3 ± 27.7*,a

Nucleus accumbens

17.3 ± 1.2

14.2 ± 1.2**,a

160.0 ± 12.7

192 ± 42.7*,a

a Nonsignificantly different from preoperative measures.

Student’s t-test: * p < 0.01; ** p < 0.001.

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published 2000