TABLE 1. Subtypes of the muscarinic receptor

Nomenclature

Molecular:

m1

m2

m3

m4

m5

Pharmacological:

M1

M2

M3

   

Selective antagonists:

Pirenzepine

AF-DX 116

HHSiD

-

-

Telenzepine

Gallamine

p-F-HHSiD

   

Tissue distribution:

Brain

Heart

Exocrine glands

Lung

 

Autonomic ganglia

Smooth muscle

Smooth muscle

Striatum

Olfactory tubercle

 

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published 2000