Figure 1.
Structure of the muscarinic receptor. Top: The sequence of the muscarinic receptor is illustrated schematically. The sequence contains seven transmembranespanning (TM) domains that are labeled with Roman numerals. The seven TM segments are connected together via three extracellular loops and three intracellular loops. The protein has an extracellular amino terminis and an intracellular carboxy terminis. Bottom: The hypothetical arrangement of the seven TM segments within the plane of the membrane.
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published 2000