Figure 1.
Regulatory pathways influencing neurotransmitter dynamics. Shown are some of the feedback loops that act to keep the output of a neuron relatively constant. These may include: (1) terminal autoreceptor regulation; (2a + 2b) terminal-terminal heteroreceptor regulation; (3a + 3b) multisynaptic feedback loops; (4) axon collaterals; (5 + 3b) dendritic-terminal heteroreceptor regulation; and (6) dendritic autoreceptor regulation. Not shown are even longer feedback systems that may involve physiological or even behavioral components.

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published 2000